We are in relentless pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a more healthy place. This was Charles Pfizer's original vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies achieve more, are more innovative, recruit and maintain the best professionals, and know how to unleash the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and demonstrates our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and embodies the value we aim to bring to patients and society. Our purpose guarantees that patients stay at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every choice we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can thrive.