We are in constant pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a better place. It was Charles Pfizer's initial vision, and it holds true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more inventive, attract and retain the best people, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that transform patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We live our purpose by finding the best science in the world, working with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.