We are in constant pursuit of breakthroughs that transform patients' lives. We innovate every day to make the world a more healthy place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies deliver better results, are more creative, draw and keep the best talent, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and demonstrates our passion for expanding our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and embodies the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We embody our purpose by sourcing the best science in the world, partnering with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to push for pro-innovation/pro-patient policies. Every choice we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.