We are in tireless pursuit of breakthroughs that transform patients' lives. We create innovations each day to make the world a more healthy place. It was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best talent, and know how to unleash the power of those team members. Pfizer's purpose—Breakthroughs that change patients' lives—powers everything we do and reflects our passion for growing our legacy as one of the most significant contributors of good to the world. Each word in our purpose has significance and embodies the value we strive to bring to patients and society. Our purpose guarantees that patients remain at the centre of all we do. We fulfill our purpose by finding the best science in the world, partnering with others in the healthcare system to enhance access to our medicines, utilizing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to create an environment where breakthroughs can flourish.