We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation every day to make the world a better place. This was Charles Pfizer's original vision, and it holds true today. Studies show what we instinctively know: that purpose-driven companies deliver better results, are more inventive, draw and keep the best talent, and know how to maximize the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and reflects our passion for growing our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We embody our purpose by seeking the best science in the world, working with others in the healthcare system to improve access to our medicines, using digital technologies to advance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.