We're in constant pursuit of breakthroughs that change patients' lives. We innovate daily to make the world a more healthy place. It was Charles Pfizer's initial vision, and it holds true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, recruit and maintain the best people, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has significance and represents the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, partnering with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.