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We are in relentless pursuit of breakthroughs that change patients' lives. We drive innovation each day to make the world a healthier place. This was Charles Pfizer's initial vision, and it still holds true today. Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best talent, and know how to unleash the power of those people. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and reflects our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has meaning and embodies the value we strive to bring to patients and society. Our purpose guarantees that patients continue to be at the core of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.