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We are in tireless pursuit of breakthroughs that change patients' lives. We drive innovation every day to make the world a better place. This was Charles Pfizer's initial vision, and it holds true today. Evidence confirms what intuition tells us: that purpose-driven companies perform better, are more creative, recruit and maintain the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—drives everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and represents the value we aim to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, working with others in the healthcare system to increase access to our medicines, utilizing digital technologies to improve our drug discovery and development, as well as patient outcomes, and driving the conversation to campaign for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to create an environment where breakthroughs can prosper.