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We are in relentless pursuit of breakthroughs that change patients' lives. We innovate each day to make the world a better place. This was Charles Pfizer's initial vision, and it still holds true today. Research confirms what we instinctively know: that purpose-driven companies perform better, are more innovative, recruit and maintain the best talent, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that improve patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and embodies the value we strive to bring to patients and society. Our purpose guarantees that patients continue to be at the centre of all we do. We live our purpose by sourcing the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and spearheading the conversation to push for pro-innovation/pro-patient policies. Every determination we make, and every move we take is done with the patient in mind—and to nurture an environment where breakthroughs can flourish.