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We are in constant pursuit of breakthroughs that improve patients' lives. We innovate every day to make the world a healthier place. It was Charles Pfizer's initial vision, and it remains true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more creative, attract and retain the best talent, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we strive to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We fulfill our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to improve our drug discovery and development, as well as patient outcomes, and leading the conversation to campaign for pro-innovation/pro-patient policies. Every choice we make, and every step we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.