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We are in tireless pursuit of breakthroughs that improve patients' lives. We create innovations each day to make the world a better place. This was Charles Pfizer's original vision, and it remains true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more creative, recruit and maintain the best people, and know how to maximize the power of those team members. Pfizer's purpose—Breakthroughs that improve patients' lives—drives everything we do and shows our passion for expanding our legacy as one of the most important contributors of good to the world. Each word in our purpose has significance and reflects the value we work to bring to patients and society. Our purpose ensures that patients continue to be at the centre of all we do. We fulfill our purpose by seeking the best science in the world, working with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.