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We are in constant pursuit of breakthroughs that change patients' lives. We drive innovation daily to make the world a better place. It was Charles Pfizer's initial vision, and it still holds true today. Studies show what we instinctively know: that purpose-driven companies perform better, are more creative, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and shows our passion for expanding our legacy as one of the most significant contributors of good to the world. Each word in our purpose has importance and reflects the value we aim to bring to patients and society. Our purpose ensures that patients remain at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and driving the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can prosper.