We are in relentless pursuit of breakthroughs that change patients' lives. We drive innovation each day to make the world a better place. It was Charles Pfizer's founding vision, and it still holds true today. Evidence confirms what we instinctively know: that purpose-driven companies perform better, are more creative, recruit and maintain the best people, and know how to maximize the power of those people. Pfizer's purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the most important contributors of good to the world. Each word in our purpose has importance and reflects the value we work to bring to patients and society. Our purpose guarantees that patients stay at the core of all we do. We fulfill our purpose by finding the best science in the world, collaborating with others in the healthcare system to enhance access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and leading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.